Thanks (again!)
Ham fisted with the keyboard so posted last reply before it was finished.
So, tried the defrag and scan with little benefit.
The start up files checked are
NvCpl...
qttask
dumprepO-K
ctfmon
googletoolbar notifier
msmgs
There are loads more listed, but not checked - think a work collegue may have tried this for me....
As for physical memory:
Total 522,672
Avail 285, 528
Cache 270,644
At the time there were 42 processes running (outlook webmail, a webpage, adobe pdf and word doc open) and cpu usage was 2%.
Does this make anything clearer??
Thanks again
A.