Hi, my latest client had the same problem. Open the PC, clear the CMOS by moving the 2-pin jumper next to the CMOS battery from positions 1-2 to 2-3. Do this while the PC is running, this will short out the PSU and computer power will switch off. Leave for 10 seconds, put back to 1-2 and use power button to restart computer. On reboot, BIOS will say 'CMOS checksum error', F1 to continue, DEL to enter BIOS. Hit DEL, then once in BIOS, F10 to save and exit. PC will then restart normally. Sounds like the problem is the ACPI controller on IRQ 9 conflicting with either the USB 1.1 host controller, or a general ACPI freeze caused by recent bootstrap change or hardware install.
Hope this helps.