I've had Rapport installed for nearly a year now and have never had any problems. From the technical information I've read about it, it looks like it is a useful addition to any PCs security. There's a guide here on how to set it up to protect other websites (such as Facebook / Hotmail / MySpace etc) Link: Setup Trusteer Rapport to protect other websites
For anti-virus software you can get a very good free program called Avast Link: avast! Free Antivirus - Download Software for Virus Protection
I also use Spyware Blaster Link: SpywareBlaster | Prevent spyware and malware. Free download.